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  • Pyxant Labs’ CRO is a high-end customer-centric bioanalytical business. At any stage in your program, our commitment is to provide you with quick, accurate results. We are confident your data will withstand any regulatory scrutiny and help you make those crucial program decisions.
  • Pyxant Labs’ CRO is a high-end customer-centric bioanalytical business. At any stage in your program, our commitment is to provide you with quick, accurate results. We are confident your data will withstand any regulatory scrutiny and help you make those crucial program decisions.
  • Pyxant Labs’ CRO is a high-end customer-centric bioanalytical business. At any stage in your program, our commitment is to provide you with quick, accurate results. We are confident your data will withstand any regulatory scrutiny and help you make those crucial program decisions.
  • Pyxant Labs’ CRO is a high-end customer-centric bioanalytical business. At any stage in your program, our commitment is to provide you with quick, accurate results. We are confident your data will withstand any regulatory scrutiny and help you make those crucial program decisions.
  • Pyxant Labs’ CRO is a high-end customer-centric bioanalytical business. At any stage in your program, our commitment is to provide you with quick, accurate results. We are confident your data will withstand any regulatory scrutiny and help you make those crucial program decisions.
  • Pyxant Labs’ CRO is a high-end customer-centric bioanalytical business. At any stage in your program, our commitment is to provide you with quick, accurate results. We are confident your data will withstand any regulatory scrutiny and help you make those crucial program decisions.

Services

Pyxant Labs is a bioanalytical contract research organization (CRO) that offers analytical research, development, and validation services to support early stage drug discovery, pre-clinical studies, and clinical trial sample analysis. Our capabilities include assays for small-molecules, antisense oligonucleotides, RNA therapeutics, gene therapy programs, and peptides in an extraordinarily wide variety of challenging biological matrices, such as plasma and different solid and liquid tissues including umbilical cord, gut slurry, and ocular tissues. We also assay custom biomarkers to both GLP and CLIA requirements.

We operate at a scale which enables a full range of mass spectrometry services alongside value-added personal service. Our customers appreciate the combination of leading science, fast response, and regulatory leadership for their bioanalytical development requirements.

Our specialized discovery team has the ability to issue data within 24 hours from the time of sample receipt. With our in-life partners, we are consistently able to provide an end-to-end service from dosing to data.
Our highly skilled and experienced scientists develop and validate customized methods within a diverse range of compound classes, as well as unique biological matrices, following guidance of various regulatory agencies including FDA (CDER, CVM), EMA, and Health Canada.
We conduct expert bioanalysis from discovery through clinical phase studies in varying compound classes, such as small molecules, RNA therapeutics (oligonucleotides), peptides, and anti-body drug conjugates (ADCs), in all biological matrices including plasma, urine, feces, and an extensive number of tissues.
Our high resolution mass spectrometry (HRMS) approach to large-molecule analysis can eliminate the need to develop suitable capture and detection reagents, as is the case for ligand binding assays. Additionally, using HRMS, we can rapidly elucidate glycosylation and phosphorylation during early-stage discovery and development. These capabilities often radically reduce development timelines and expenses for molecules and binding moieties ranging beyond 300,000 Da. Early-stage discovery and mechanistic confirmations can sometimes be accomplished in as little as two weeks with our mass spectrometry approach, rather than six months if binding antibody production is required.

Proprietary Methods

Please, contact us if your compound is not on this list.


Tables below scroll left or right.

Bioanalytical Method Matrix Method Range Sample Volume
Acyclovir aka Aciclovir Skin (Franz Cell
Receptor Fluid)
1 to 1,000 ng/mL 50 µL
Acepromazine aka Acetylpromazine Canine Plasma 1 to 1,000 ng/mL 25 µL
Acetaminophen Human Plasma 250 to 10,000 ng/mL 25 µL
Atazanavir Human Plasma 10 to 10,000 ng/mL 50 µL
Atomoxetine Human Plasma 1 to 1,000 ng/mL 50 µL
ATRIPLA™ (Tenofovir, Emtricitabine, Efavirenz) Human Plasma 5 to 5,000 ng/mL 50 µL
Azithromycin Feline Plasma 100 to 100,000 ng/mL 50 µL
Broflanilide Bovine Plasma/Tissue 0.5 to 500 ng/mL 100 µL
Budesonide Human Plasma 10 to 750 pg/mL 150 µL
Buprenorphine Rabbit/Rat/Mouse Plasma 0.5 to 100 ng/mL 50 µL
Capsaicin Human Plasma 0.05 to 50 ng/mL 100 µL
Captisol® Human Plasma 2 to 200 µg/mL 50 µL
Carprofen Canine Plasma 100 to 75,000 ng/mL 50 µL
Clarithromycin Feline Plasma 1 to 1,000 ng/mL 25 µL
Clomipramine Canine Plasma 0.5 to 250 ng/mL 50 µL
Darunavir Human Plasma 10 to 10,000 ng/mL 50 µL
Deracoxib Canine Plasma 10 to 5,000 ng/mL 50 µL
Deracoxib Tramadol, Concurrent Assay Canine Plasma 10 to 5,000 ng/mL
10 to 1,000 ng/mL
50 µL
Detomidine Equine Plasma 1 to 1,000 ng/mL 25 µL
Dextromethorphan Human Plasma 1 to 500 ng/mL 50 µL
Dextromethorphan Human Urine 1 to 500 ng/mL 50 µL
Dextrorphan Human Plasma 1 to 500 ng/mL 50 µL
Dextrorphan Human Urine 1 to 500 ng/mL 50 µL
Diclofenac Beagle Plasma 1 to 1,000 ng/mL 150 µL
Digoxin Human Plasma 100 to 50,000 ng/mL 50 µL
Drontal Plus: Praziquantel and Pyrantel Pamoate Beagle Plasma 0.5 to 1,000 ng/mL 50 µL
Enrofloxacin Canine/Feline Plasma 2 to 2,000 ng/mL 50 µL
Fenbendazole Equine Plasma 1 to 1,000 ng/mL 50 µL
Floxuridine (Free and Total) Monkey Plasma 5 to 1,000 ng/mL 25 µL
Flunixin Equine Plasma 1 to 1,000 ng/mL 25 µL
Fluoxetine Human Plasma 0.1 to 50 ng/mL 150 µL
Gemfibrozil Human Plasma 50 to 50,000 ng/mL 25 µL
Granisetron Beagle/Pig Plasma 0.05 to 50 ng/mL 100 µL
Bioanalytical Method Matrix Method Range Sample Volume
Hydrochlorothiazide aka HCTZ, HCT, HCZ Human Plasma 1 to 250 ng/mL 300 µL
Hyrocodone Human Plasma 0.75 to 50 ng/mL 100 µL
Indomethacin aka Indometacin Beagle Plasma 1 to 1,000 ng/mL 150 µL
Ketoconazole Human Plasma 20 to 10,000 ng/mL 50 µL
Latanoprost and latanoprost Free Acid Human/Minipig/Rabbit Plasma 50 to 1,500 pg/mL 250 µL
Lisdexamphetamine d-Amphetamine Human Plasma 0.25 to 100 ng/mL
1 to 100 ng/mL
50 µL
Methotrexate aka Amethopterin Human Plasma 1 to 200 ng/mL 200 µL
Methamizole Feline Plasma 2 to 2,000 ng/mL 50 µL
Methylphenidate Human Plasma 0.05 to 25 ng/mL 100 µL
Metoprolol Human Plasmaa 0.25 to 250 ng/mL 100 µL
Midazolam and α-Hydroxymidazolam Human Plasma 0.1 to 100 ng/mL 100 µL
Milbemycin Oxime Canine/Feline Plasma 10 to 2,000 ng/mL 50 µL
Montelukast and Montelukast 1,2-diol Human Plasma 5 to 1,000 ng/mL 50 µL
Moxidectin Human Plasma 0.5 to 100 ng/mL 100 µL
Nitroglycerin, 1,2 Dinitroglycerin, 1,3 Dinitroglycerin Human Plasma 20 to 8,000 ng/mL 250 µL
Norfluoxetine aka Seproxetine Human Plasma 0.1 to 50 ng/mL 150 µL
Olanzapine Beagle Plasma 0.1 to 50 ng/mL 100 µL
Omeprazole Equine Plasma 1 to 1,000 ng/mL 25 µL
Phenylbutazone Equine Plasma 25 to 5,000 ng/mL 200 µL
Phenylpropanolamine Canine Plasma 1 to 1,000 ng/mL 25 µL
Raltegravir Human Plasma 10 to 10,000 ng/mL 50 µL
Rosiglitazone Minipig/Human Plasma 50 to 5,000 ng/mL 75 µL
Roxithromycin Feline Plasma 100 to 50,000 ng/mL 25 µL
Scopolamine Human Plasma 0.002 to 2 ng/mL 300 µL
Sildenafil and N-desmethyl Sildenafil Human Plasma 0.5 to 500 ng/mL 50 µL
Sofosbuvir and GS331007 Human Plasma 2 to 2,000 ng/mL 50 µL
Sulfadiazine Trimethoprim Equine Plasma 100 to 10,000 ng/mL
10 to 1000 ng/mL
50 µL
Tapentadol Human Plasma 0.2 to 200 ng/mL 50 µL
Telmisartan Human Plasma 0.5 to 5,000 ng/mL 25 µL
Tivozanib Rabbit Plasma/Tissue 0.1 to 50 ng/mL 50 µL
Topiramate Human Plasma 5 to 750 ng/mL 50 µL
Triamcinolone Acetate Human Plasma 1 to 500 ng/mL 200 µL
Valdecoxib Human Plasma 0 to 300 ng/mL 500 µL

Quality & Compliance


Quality Assurance & Reporting

Our in-house Quality Assurance department oversees the integrity of all the data we generate and the reports we publish. Pyxant Labs' QA team is set up to simulate an on-site FDA audit team, ensuring we adhere to the latest guidance. GLP studies are run against a set of standard operating procedures by staff who have received extensive training on all aspects of the study.

Additionally, our Quality Assurance Manager is a member of the GLP section and a co-chair of the Bioanalytical Specialty section for the Society of Quality Assurance and is a member of the Rocky Mountain Regional Chapter of the Society of Quality Assurance. Moreover, our Laboratory Direct has been a member of the Global CRO Council (GCC) since its inception.

Besides regular internal audits, Pyxant Labs always welcomes audits and site inspections from existing and potential clients. We have had multiple inspections to date by the FDA (CDER, CVM), which resulted in no findings impacting data quality.

We have a dedicated technical team assigned to reporting and offering customized reports on a project-by-project basis.

Customer Service Team

 
You will often find our customer service team members at conferences or at meetings, exchanging knowledge and networking with those in the industry. If you happen to be at the same event, feel free to reach out to us for a meeting, or stop by our table if we’re exhibiting.
Customer Service Team

Adam Winstrom

Business Development Manager

Michael Olson

Director of Business Development

Pam Stevenson

Director of Business Development

Olivia Franks

Client Manager

Kathryn Sears

Senior Program Manager

Jeremy Thompson

Senior Program Manager

Cassidy Hatch

Study Coordinator

Kylie Smith

Study Coordinator

Careers

Pyxant Labs is a dynamic company encompassing a growing contract research organization specializing in GLP bioanalytical support and a clinical toxicology laboratory specializing in developing and delivering premium drug testing services to the medical industry. Our core focus is on customer service, as well as regulatory and technical expertise, structured to create industry leading customer satisfaction.

We recognize experienced and highly qualified team players are essential to the success of our company. The only way to deliver on our objectives is to recruit, develop, and retain exceptional people. Our human resources management practices, including training, role design, project assignments, and infrastructure, contribute to a successful employee experience.

Current Positions

Pyxant CRO analyzing vials

Contact Us

Contact Our Contract Research Organization

We are located in Colorado Springs, CO conveniently close to downtown and I-25.

From I-25, head west on Garden of the Gods Road, turn right on Forge Road, then turn left at 4720 Forge Road, Suite 106, Colorado Springs, CO 80907.

Our staff is always available for questions. Call us during business hours, or e-mail us anytime.

Phone: +1 (719) 593-1165
Fax: +1 (719) 593-1625
E-mail: info@pyxant.com